Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 4/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69514 | 0.77 | SMN1; SMN2 (0.40) | ALDH1A1HSD17B10SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL2821405 | 0.77 | NOTUM (0.38) | ALDH1A1L3MBTL1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17540870 | 0.73 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL8585255 | 0.67 | CHRM2 (0.36) | ALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL3758938 | 0.67 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL2182857 | 0.65 | KDM4E (0.48) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL31607672 | 0.65 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL169281 | 0.65 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL29793563 | 0.65 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL10995283 | 0.65 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1HSD17B10SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010075356-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-07-01 | — | — | WO | disclosed |
| US-20100160323-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160323-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | ALDH1A1 969/4885L3MBTL1 4330/4885HSD17B10 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.