Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 9/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962391 | 0.88 | FASN (0.64) | FASNHSD17B3ALDH1A1TSHRHPGD | |
| SCHEMBL4742082 | 0.78 | FASN (0.63) | FASN | |
| SCHEMBL28410108 | 0.77 | FASN (0.46) | FASNHSD17B3ALDH1A1TSHRHPGD | |
| SCHEMBL30212099 | 0.75 | FASN (0.91) | FASNHSD17B3ALDH1A1TSHRHPGD | |
| SCHEMBL1785484 | 0.74 | FASN (0.60) | FASN | |
| SCHEMBL8571259 | 0.72 | FASN (0.51) | FASN | |
| SCHEMBL30212096 | 0.72 | FASN (1.00) | FASNHSD17B3SMN1; SMN2 | |
| SCHEMBL30212094 | 0.72 | FASN (0.68) | FASNALDH1A1POLB | |
| SCHEMBL30212070 | 0.71 | FASN (0.82) | FASNSMN1; SMN2 | |
| SCHEMBL31328339 | 0.68 | PTGES (0.53) | FASNHSD17B3RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997099-A | A kind of fully synthetic new method of natural products flavaspidic acid BB | 中国药科大学 | 2018-12-14 | — | — | CN | claimed |
| CN-107837247-A | Dryopteris fragrans phloroglucinol compound flavaspidic acid BB and its antibacterial applications | 广东药科大学 | 2018-03-27 | — | — | CN | claimed |
| CN-107837247-B | Dryopteris fragrans phloroglucinol compound yellow-sheep-maleic acid BB and antibacterial application thereof | 广东药科大学 | 2020-06-05 | — | — | CN | disclosed |
| CN-107837247-A | Dryopteris fragrans phloroglucinol compound flavaspidic acid BB and its antibacterial applications | 广东药科大学 | 2018-03-27 | — | — | CN | disclosed |