Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844879 | 0.77 | CHRNB2 (0.60) | ALDH1A1MEN1KMT2AHDAC6 | |
| SCHEMBL18397694 | 0.77 | POLB (0.44) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7842881 | 0.76 | ALDH1A1 (0.46) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28807651 | 0.75 | CHRM1 (0.50) | CHRM1KDM4EALDH1A1CHRM2CHRM4 | |
| SCHEMBL12674832 | 0.73 | NPC1 (0.42) | MEN1KMT2ANPC1HDAC6CNR1 | |
| SCHEMBL4817596 | 0.73 | PTPRC (0.50) | ALDH1A1 | |
| SCHEMBL21471348 | 0.73 | PARP1 (0.53) | KDM4EALDH1A1NPC1 | |
| SCHEMBL7836093 | 0.72 | CYP3A4 (0.57) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL569778 | 0.71 | ALDH1A1 (0.47) | ALDH1A1POLB | |
| SCHEMBL31032281 | 0.71 | ALDH1A1 (0.47) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848941-A | Align 2,3 indanyls and 1,2,3,4 tetrahydronaphthalene radical derivatives of substitution | 巴斯夫欧洲公司 | 2018-03-27 | — | — | CN | disclosed |