Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831144 | 0.85 | — | — | |
| SCHEMBL28275959 | 0.82 | KDM4E (0.36) | KDM4EKMT2A | |
| SCHEMBL26633641 | 0.82 | KDM4E (0.40) | KDM4EKMT2A | |
| SCHEMBL28589924 | 0.81 | — | — | |
| SCHEMBL16914222 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL3493468 | 0.79 | KDM4E (0.34) | KDM4EKMT2A | |
| SCHEMBL12989448 | 0.79 | LMNA (0.32) | — | |
| SCHEMBL3831050 | 0.76 | KDM4E (0.31) | KDM4E | |
| SCHEMBL2080000 | 0.76 | — | — | |
| SCHEMBL28515873 | 0.72 | KDM4E (0.41) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057689-A | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-109415360-B | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113214246-A | Protein kinase C inhibitors and methods of their use | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-106795151-B | Protein kinase C inhibitors and methods of their use | 诺华股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112625028-A | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-107922388-B | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-109415360-A | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-107922388-A | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2018-04-17 | — | — | CN | disclosed |