Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28140675 | 0.75 | MEN1 (0.49) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6128160 | 0.75 | KDM1A (0.53) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL5514976 | 0.74 | MAPT (0.48) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL8372603 | 0.73 | MAPT (0.48) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL3198336 | 0.73 | ALPI (0.52) | MAPT | |
| SCHEMBL1339972 | 0.73 | ALPI (0.52) | MAPT | |
| SCHEMBL555036 | 0.71 | MAPT (0.50) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL5763729 | 0.71 | EPHX1 (0.58) | ALDH1A1EPHX1 | |
| SCHEMBL412018 | 0.71 | MAPT (0.50) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL239274 | 0.71 | MAPT (0.50) | MAPTLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418506-B | Acetobenzylamide piperazine derivative and its application as neuroprotection agent | 上海医药工业研究院 | 2018-04-24 | — | — | CN | disclosed |