SCHEMBL5514976

SCHEMBL5514976

O=C(O)C(CNc1ccccc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 3/20 0.44
TP53 P04637 1/20 0.44
EPHX1 P07099 1/20 0.44
TSHR P16473 1/20 0.44
EPHX2 P34913 1/20 0.44
CDK9 P50750 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
CASP3 P42574 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
DNM1 Q05193 1/20 0.43
KDM4E B2RXH2 2/20 0.43
LMNA P02545 2/20 0.43
GAA P10253 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
FFAR1 O14842 1/20 0.43
MAPK13 O15264 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL555036 0.83 MAPT (0.50) MAPTSMN1; SMN2HTTALDH1A1TP53
SCHEMBL239274 0.83 MAPT (0.50) MAPTSMN1; SMN2HTTALDH1A1TP53
SCHEMBL412018 0.83 MAPT (0.50) MAPTSMN1; SMN2HTTALDH1A1TP53
SCHEMBL2507158 0.81 APAF1 (0.58) MAPTSMN1; SMN2HTTALDH1A1LMNA
Hydrochloric Acid SCHEMBL6422363 0.81 MAPT (0.49) MAPTSMN1; SMN2HTTALDH1A1TP53
SCHEMBL16165637 0.81 APAF1 (0.58) MAPTSMN1; SMN2HTTALDH1A1LMNA
SCHEMBL8795979 0.81 ALDH1A1 (0.44) MAPTSMN1; SMN2HTTALDH1A1LMNA
SCHEMBL3198336 0.81 ALPI (0.52) MAPT
Hydrochloric Acid SCHEMBL1140275 0.81 MAPT (0.49) MAPTSMN1; SMN2HTTALDH1A1TP53
SCHEMBL1339972 0.81 ALPI (0.52) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed