Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412018 | 1.00 | MAPT (0.50) | MAPTSMN1; SMN2HTTDNM1LMNA | |
| SCHEMBL239274 | 1.00 | MAPT (0.50) | MAPTSMN1; SMN2HTTDNM1LMNA | |
| Hydrochloric Acid SCHEMBL1140275 | 0.98 | MAPT (0.49) | MAPTSMN1; SMN2HTTDNM1LMNA | |
| Hydrochloric Acid SCHEMBL6422363 | 0.98 | MAPT (0.49) | MAPTSMN1; SMN2HTTDNM1LMNA | |
| Phosphoric Acid SCHEMBL8362755 | 0.85 | MAPT (0.43) | MAPTSMN1; SMN2HTTDNM1LMNA | |
| SCHEMBL5514976 | 0.83 | MAPT (0.48) | MAPTSMN1; SMN2HTTDNM1LMNA | |
| SCHEMBL12227832 | 0.82 | FDPS (0.54) | SMN1; SMN2HTTLMNAKDM4EPTPRA | |
| SCHEMBL14157786 | 0.82 | MAPT (0.44) | MAPTHTTLMNAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL4829746 | 0.81 | MAPT (0.42) | MAPTHTTLMNAKDM4EMEN1 | |
| SCHEMBL6086624 | 0.81 | MAPT (0.57) | MAPTSMN1; SMN2HTTDNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633326-B2 | Method for preparing taxane derivatives | SAMYANG BIOPHARMACEUTICALS CORPORATION (KR) | 2014-01-21 | — | — | US | claimed |
| US-20120035379-A1 | METHOD FOR PREPARING TAXANE DERIVATIVES | SAMYANG GENEX CORPORATION (KR) | 2012-02-09 | — | — | US | claimed |
| WO-2010123186-A1 | METHOD FOR PREPARING TAXANE DERIVATIVES | SAMYANG GENEX CORPORATION (KR) | 2010-10-28 | — | — | WO | claimed |
| US-20170342451-A1 | BIOSYNTHESIS OF PACLITAXEL INTERMEDIATE | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2017-11-30 | — | — | US | disclosed |
| US-9732365-B2 | Biosynthesis of paclitaxel intermediate | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2017-08-15 | — | — | US | disclosed |
| US-20150284751-A1 | BIOSYNTHESIS OF PACLITAXEL INTERMEDIATE | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2015-10-08 | — | — | US | disclosed |
| US-8633326-B2 | Method for preparing taxane derivatives | SAMYANG BIOPHARMACEUTICALS CORPORATION (KR) | 2014-01-21 | — | — | US | disclosed |
| US-20120035379-A1 | METHOD FOR PREPARING TAXANE DERIVATIVES | SAMYANG GENEX CORPORATION (KR) | 2012-02-09 | — | — | US | disclosed |
| WO-2010123186-A1 | METHOD FOR PREPARING TAXANE DERIVATIVES | SAMYANG GENEX CORPORATION (KR) | 2010-10-28 | — | — | WO | disclosed |
| EP-1463699-A2 | PROCESS FOR THE PRODUCTION OF 3-PHENYLISOSERINE | ALTANA Pharma AG (DE) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003003804-A3 | PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE 3-PHENYLISOSERINE | ALTANA PHARMA AG (DE) | 2004-07-01 | — | — | WO | disclosed |
| WO-2003003804-A2 | PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE 3-PHENYLISOSERINE | ALTANA PHARMA AG (DE) | 2003-01-16 | — | — | WO | disclosed |
| US-5470866-A | Method for the conversion of cephalomannine to taxol and for the preparation of n-acyl analogs of taxol | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (US) | 1995-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035379-A1 | METHOD FOR PREPARING TAXANE DERIVATIVES | PTMA, TNPO3, ACR | MAPT 737/4885SMN1; SMN2 2678/4885HTT 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.