SCHEMBL28213629

SCHEMBL28213629

CC(C)(C)c1cccc(C(C)(C)C)c1OC(c1ccccc1)C(CO)(CO)CO

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.35
TSHR P16473 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
RIPK1 Q13546 2/20 0.33
AOC3 Q16853 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
NR1H4 Q96RI1 1/20 0.32
NLRP3 Q96P20 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28273733 0.86 MAOB (0.32) CA2NR1H4
SCHEMBL1031459 0.84 CA2 (0.37) CA2TSHRALDH1A1TDP1GABRA1
SCHEMBL4418368 0.81 CA2 (0.34) CA2TSHRALDH1A1TDP1GABRA1
SCHEMBL4200174 0.81 CA2 (0.34) CA2TSHRALDH1A1TDP1GABRA1
SCHEMBL999178 0.78 ALDH1A1 (0.35) CA2TSHRCYP2C9CYP2C19ALDH1A1
SCHEMBL9249443 0.77 ALDH1A1 (0.40) CA2TSHRCYP1A2CYP3A4CYP2C9
SCHEMBL6744160 0.75 ALDH1A1 (0.33) CYP3A4ALDH1A1TDP1KDM4EGAA
Pyrophosphoric Acid SCHEMBL12980964 0.75 NR1H4 (0.31) CA2NR1H4NLRP3
SCHEMBL27801952 0.75 MEN1 (0.31) CA2TSHRCYP1A2CYP3A4CYP2C9
SCHEMBL1029655 0.75 SLC6A4 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110506079-A POLYAMIDE COMPOSITION AND MOLDED ARTICLE ASAHI CHEMICAL IND 2019-11-26 CN disclosed
CN-105849196-B Daiamid composition, products formed, LED reflecting plates and the method for suppressing the reflectivity reduction as caused by heat 旭化成株式会社 2018-04-03 CN disclosed