Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14556308 | 0.82 | MAPT (0.50) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL4915335 | 0.81 | MAPT (0.53) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL11787514 | 0.79 | ALDH1A1 (0.50) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL14626606 | 0.79 | MAPT (0.47) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL17106594 | 0.76 | MAPT (0.45) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL7758231 | 0.76 | MAPT (0.45) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL2027813 | 0.76 | MAPT (0.45) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL735218 | 0.76 | MAPT (0.45) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL11592383 | 0.76 | NPC1 (0.50) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL17789917 | 0.76 | HSD17B10 (0.48) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108003073-A | preparation method of amino phenyl- β -hydroxyethyl sulfone and p-aminophenyl- β -hydroxyethyl sulfone sulfonate | 广东众和化塑有限公司 | 2018-05-08 | — | — | CN | disclosed |