Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332168 | 0.84 | MAPT (0.44) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL14556308 | 0.81 | MAPT (0.50) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL4915335 | 0.79 | MAPT (0.53) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL11787514 | 0.78 | ALDH1A1 (0.50) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL14626606 | 0.78 | MAPT (0.47) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL28213828 | 0.76 | MAPT (0.46) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL17106594 | 0.75 | MAPT (0.45) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL735218 | 0.75 | MAPT (0.45) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL2027813 | 0.75 | MAPT (0.45) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL11592383 | 0.75 | NPC1 (0.50) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661291-B1 | Solid phase synthesis of oligoribonucleotide | AVENTIS PHARMA GMBH (DE) | 2001-03-07 | — | — | EP | disclosed |
| EP-0661291-A1 | Solid phase synthesis of oligoribonucleotide | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |