SCHEMBL28214

SCHEMBL28214

COC[C@]1(c2ccc(C)c(Cc3ccc(O)cc3)c2)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.45
SLC5A1 P13866 12/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3194431 0.84 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL17993 0.84 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL46243 0.83 SLC5A2 (0.49) SLC5A2SLC5A1
SCHEMBL46177 0.83 SLC5A2 (0.49) SLC5A2SLC5A1
SCHEMBL2861270 0.82 SLC5A2 (0.46) SLC5A2SLC5A1
SCHEMBL46297 0.78 SLC5A2 (0.60) SLC5A2SLC5A1
SCHEMBL21125851 0.77 SLC5A2 (0.53) SLC5A2SLC5A1
SCHEMBL19201012 0.75 SLC5A2 (0.54) SLC5A2SLC5A1
SCHEMBL12363977 0.73 SLC5A2 (0.48) SLC5A2SLC5A1
SCHEMBL14209303 0.73 SLC5A2 (0.48) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025857-A1 CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS HETERO RESEARCH FOUNDATION (IN) 2012-03-01 WO disclosed