SCHEMBL46177

SCHEMBL46177

CCc1ccc(Cc2cc([C@@]3(COC)O[C@@H](CO)[C@@H](O)[C@H](O)[C@H]3I)ccc2C)cc1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.49
SLC5A1 P13866 12/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL46243 1.00 SLC5A2 (0.49) SLC5A2SLC5A1
SCHEMBL28214 0.83 SLC5A2 (0.45) SLC5A2SLC5A1
SCHEMBL46238 0.77 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL10073324 0.77 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL46297 0.72 SLC5A2 (0.60) SLC5A2SLC5A1
SCHEMBL3194431 0.72 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL17993 0.72 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL19201012 0.71 SLC5A2 (0.54) SLC5A2SLC5A1
SCHEMBL12363978 0.70 SLC5A2 (0.46) SLC5A2SLC5A1
SCHEMBL12363977 0.69 SLC5A2 (0.48) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012003811-A1 C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD ZHEJIANG BETA PHARMA INC. (CN) 2012-01-12 WO disclosed