Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295106 | 0.64 | NISCH (0.35) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21900389 | 0.61 | — | — | |
| SCHEMBL23969743 | 0.58 | IDH1 (0.31) | KDM4EALDH1A1MAPTHTR1AHTR7 | |
| SCHEMBL28853621 | 0.58 | NPC1 (0.32) | — | |
| SCHEMBL28347989 | 0.58 | PTPRC (0.34) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27845727 | 0.58 | BCHE (0.30) | — | |
| SCHEMBL197834 | 0.58 | ACHE (0.47) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29547174 | 0.58 | ACHE (0.47) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29979935 | 0.56 | MEN1 (0.44) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL10700223 | 0.56 | ACHE (0.45) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193750-B | Suppress mitotic Compounds and methods for by suppressing aurora kinase | 千禧药品公司 | 2018-04-27 | — | — | CN | disclosed |