Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27855880 | 0.79 | CYP1A2 (0.33) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL1057092 | 0.75 | CYP1A2 (0.31) | MEN1KMT2AALDH1A1MAPTHTT | |
| Lithium Ion SCHEMBL29363019 | 0.74 | KDM4E (0.31) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7883081 | 0.72 | CYP1A2 (0.36) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7080326 | 0.70 | KDM4E (0.32) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL27604068 | 0.70 | CYP1A2 (0.33) | MEN1KMT2ACYP1A2CYP2D6ALOX15 | |
| SCHEMBL28230720 | 0.69 | SETD7 (0.38) | MEN1KMT2AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL219752 | 0.69 | TSHR (0.36) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7214854 | 0.68 | ALDH1A1 (0.38) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL11067247 | 0.66 | KDM4E (0.53) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315551-A1 | 2-ALKYLCARBONYL[2,3-b]FURAN-4,9-DIONE PRODUCTION METHOD AND PRODUCTION INTERMEDIATE THEREFOR | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315551-A1 | 2-ALKYLCARBONYL[2,3-b]FURAN-4,9-DIONE PRODUCTION METHOD AND PRODUCTION INTERMEDIATE THEREFOR | WEE2, DHPS, WEE1 | MEN1 2091/4885KMT2A 1608/4885KDM4E 3625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.