SCHEMBL28214548

SCHEMBL28214548

CC=Cc1ccc(-c2ccc(O)cc2)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGES O14684 7/20 0.51
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 1/20 0.51
ALDH1A1 P00352 1/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
MAPK1 P28482 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
CNR2 P34972 1/20 0.50
ESR2 Q92731 2/20 0.49
PELI1 Q96FA3 2/20 0.46
HSD17B1 P14061 1/20 0.46
ESR1 P03372 1/20 0.46
BACE1 P56817 1/20 0.42
ALOX5 P09917 1/20 0.41
TYR P14679 1/20 0.41
LCK P06239 1/20 0.39
NQO2 P16083 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4894861 0.81 ALDH5A1 (0.52) KDM4EALDH1A1HPGDESR2PELI1
SCHEMBL4892005 0.78 ESR2 (0.47) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL4892009 0.78 ESR2 (0.47) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL29738442 0.77 ESR2 (0.76) ESR2HSD17B1ESR1ALOX5
SCHEMBL439874 0.77 ESR2 (0.76) ESR2HSD17B1ESR1ALOX5
SCHEMBL28238194 0.77 PTGES (0.53) PTGESKDM4EMEN1ALDH1A1MAPT
SCHEMBL18199531 0.77 PTGES (0.53) PTGESKDM4EMEN1ALDH1A1MAPT
SCHEMBL15385655 0.76 TYR (0.57) PTGESKDM4EMEN1ALDH1A1MAPT
SCHEMBL2718119 0.75 ESR2 (0.73) ESR2HSD17B1ESR1
SCHEMBL1397053 0.74 APP (0.59) PTGESKDM4EMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104205376-B LED device and for producing its method for including transition material chemistry 沙特基础全球技术有限公司 2018-04-27 CN disclosed