Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105243 | 0.87 | EPHX2 (0.46) | GAAKDM4EMAPK1DRD2DRD3 | |
| SCHEMBL27756054 | 0.83 | KDM4E (0.53) | GAAKDM4EMAPK1DRD2DRD3 | |
| SCHEMBL26120478 | 0.78 | CCNK (0.47) | HTT | |
| SCHEMBL23236309 | 0.77 | KAT2B (0.38) | — | |
| SCHEMBL17506389 | 0.77 | SHMT2 (0.46) | GAAHDAC6HDAC8L3MBTL1KMT2A | |
| SCHEMBL27227643 | 0.74 | CCNK (0.35) | — | |
| SCHEMBL28171097 | 0.74 | KDM4E (0.55) | GAAKDM4EMAPK1DRD2DRD3 | |
| SCHEMBL23236057 | 0.73 | DPP4 (0.47) | MAPK1ALDH1A1HTTL3MBTL1KMT2A | |
| SCHEMBL1740546 | 0.72 | PDE10A (0.40) | KDM4EALDH1A1L3MBTL1KMT2ACYP2C19 | |
| SCHEMBL27225973 | 0.71 | CCNK (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026085-A | Fumidil alcohol heterocyclic compound and preparation and use its method | 扎夫根股份有限公司 | 2018-05-11 | — | — | CN | disclosed |