Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28859486 | 0.81 | GPR84 (0.41) | GPR84HTR2AFFAR1KDM4EATM | |
| SCHEMBL28919212 | 0.75 | GPR84 (0.47) | GPR84HTR2AKDM4EATMMAPT | |
| SCHEMBL28214828 | 0.75 | ATM (0.42) | GPR84HTR2AKDM4EATMMAPT | |
| SCHEMBL14665073 | 0.73 | HTR2A (0.67) | GPR84HTR2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL17242302 | 0.69 | GPR84 (0.69) | GPR84HTR2AFFAR1ATMMAPT | |
| SCHEMBL28907736 | 0.68 | ATM (0.52) | GPR84HTR2AFFAR1ATMMAPT | |
| SCHEMBL11526080 | 0.68 | ATM (0.52) | GPR84HTR2AFFAR1ATMMAPT | |
| SCHEMBL6139054 | 0.68 | GPR84 (0.65) | GPR84HTR2AFFAR1SMN1; SMN2MAPT | |
| SCHEMBL7005714 | 0.65 | GPR84 (1.00) | GPR84HTR2AFFAR1KDM4EATM | |
| SCHEMBL28780556 | 0.65 | MAPK1 (0.46) | GPR84HTR2AFFAR1ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047118-A | The synthetic method of 3- indoles seleno alcohols organic compounds | 温州大学苍南研究院 | 2018-05-18 | — | — | CN | disclosed |