SCHEMBL28907736

SCHEMBL28907736

c1ccc2c([Se]c3c[nH]c4ccccc34)c[nH]c2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.52
GPR84 Q9NQS5 3/20 0.50
MEN1 O00255 2/20 0.50
CYP3A4 P08684 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPT P10636 1/20 0.50
AHR P35869 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
IMPDH2 P12268 3/20 0.47
CYP2A6 P11509 2/20 0.47
IMPDH1 P20839 1/20 0.47
MPO P05164 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
NFKB1 P19838 1/20 0.44
HTR1D P28221 1/20 0.44
HTR1B P28222 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
HTR7 P34969 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28827211 0.87 ATM (0.45) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL11526080 0.86 ATM (0.52) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL28616115 0.77 IMPDH2 (0.53) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL28919212 0.77 GPR84 (0.47) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL28780556 0.77 MAPK1 (0.46) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL188194 0.73 ATM (0.54) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL30914580 0.73 MAPK1 (0.47) GPR84MEN1KMT2AMAPTNFKB1
SCHEMBL1202543 0.72 IMPDH2 (0.63) ATMGPR84MEN1CYP3A4KMT2A
Hydrochloric Acid SCHEMBL28905061 0.71 ATM (0.52) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL27981638 0.71 GPR84 (0.77) ATMGPR84MEN1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286555-A Synthetic method of 3-alkynylselendole compound 温州医科大学 2022-11-04 CN disclosed