SCHEMBL28214835

SCHEMBL28214835

O=C(O)N1CCN(C(=O)ON2CCNCC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
CHKA P35790 1/20 0.35
CHRNB2 P17787 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
CHRNB3 Q05901 1/20 0.34
CHRNA6 Q15825 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
TPSAB1 Q15661 2/20 0.32
TPSD1 Q9BZJ3 2/20 0.32
TPSG1 Q9NRR2 2/20 0.32
POLB P06746 1/20 0.31
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28094583 0.88 CA2 (0.46) CA2CA12CA1CA9CHKA
SCHEMBL19066161 0.82 CA2 (0.55) CA2CA12CA1CA9CHKA
SCHEMBL6844025 0.79 CA2 (0.54) CA2CA12CA1CA9CHKA
SCHEMBL31040426 0.79 CA2 (0.54) CA2CA12CA1CA9CHKA
SCHEMBL31505510 0.77 CA2 (0.52) CA2CA12CA1CA9CHKA
SCHEMBL32689447 0.77 CA2 (0.52) CA2CA12CA1CA9CHKA
SCHEMBL15319 0.76
SCHEMBL6961568 0.76
SCHEMBL17100538 0.76 CA2 (0.56) CA2CA12CA1CA9CHKA
SCHEMBL4958163 0.74 CA2 (0.39) CA2CA12CA1CA9CHKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108026085-A Fumidil alcohol heterocyclic compound and preparation and use its method 扎夫根股份有限公司 2018-05-11 CN disclosed