Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975200 | 0.83 | TSHR (0.41) | TDP1MAPTTSHRCACNA1BAPBA1 | |
| SCHEMBL6696365 | 0.79 | SMN1; SMN2 (0.43) | TSHRKMT2AALDH1A1PTPRBSMN1; SMN2 | |
| SCHEMBL452543 | 0.79 | TDP1 (0.43) | TDP1MAPTTSHRCACNA1BAPBA1 | |
| SCHEMBL6286535 | 0.76 | TDP1 (0.41) | TDP1MAPTTSHRCACNA1BAPBA1 | |
| SCHEMBL31443227 | 0.75 | TDP1 (0.43) | TDP1MAPTTSHRCACNA1BAPBA1 | |
| SCHEMBL14331822 | 0.74 | TSHR (0.46) | TDP1MAPTTSHRCACNA1BAPBA1 | |
| SCHEMBL28206 | 0.73 | — | — | |
| SCHEMBL20727109 | 0.73 | TDP1 (0.39) | TDP1MAPTTSHRCACNA1BAPBA1 | |
| SCHEMBL28214870 | 0.71 | MAPT (0.38) | TDP1MAPTTSHRCACNA1BAPBA1 | |
| SCHEMBL28832801 | 0.71 | TDP1 (0.43) | TDP1MAPTTSHRCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047268-A | A kind of miscellaneous two ring of -5- alkyl [3.3.3] the hendecane class compound of 1- azepines -5- germanium, synthetic method and application | 中国科学技术大学 | 2018-05-18 | — | — | CN | disclosed |