Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19105301 | 0.90 | TSHR (0.42) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| SCHEMBL452544 | 0.90 | ALDH1A1 (0.41) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4766772 | 0.82 | TSHR (0.42) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| SCHEMBL20954020 | 0.82 | TSHR (0.40) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| SCHEMBL4773694 | 0.80 | ALDH1A1 (0.37) | TSHRMAPTALDH1A1CYP3A4LMNA | |
| SCHEMBL32679948 | 0.79 | TSHR (0.43) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| SCHEMBL11738530 | 0.78 | ALDH1A1 (0.36) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4767559 | 0.78 | CASP1 (0.35) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| SCHEMBL20241539 | 0.78 | CA12 (0.35) | TSHRMAPTALDH1A1CYP3A4LMNA | |
| SCHEMBL28431074 | 0.77 | TSHR (0.37) | TSHRTDP1MAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001072704-A1 | AZETIDINONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A METHOD FOR PRODUCING 1-β-ALKYL AZETIDINONE USING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2001-10-04 | — | — | WO | claimed |
| CN-102083798-B | With the ruthenium olefin metathesis catalyst with the N-heterocyclic carbene ligand replacing skeleton | 马特里亚公司 | 2016-10-26 | — | — | CN | disclosed |
| WO-2001072704-A1 | AZETIDINONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A METHOD FOR PRODUCING 1-β-ALKYL AZETIDINONE USING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2001-10-04 | — | — | WO | disclosed |