Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394257 | 0.83 | TDP1 (0.40) | TDP1TSHRALDH1A1LMNAMAPT | |
| SCHEMBL23781344 | 0.83 | TDP1 (0.40) | TDP1TSHRALDH1A1LMNAMAPT | |
| SCHEMBL19105432 | 0.83 | TSHR (0.43) | TDP1TSHRALDH1A1LMNAMAPT | |
| SCHEMBL20727109 | 0.81 | TDP1 (0.39) | TDP1TSHRALDH1A1LMNAMAPT | |
| SCHEMBL19105329 | 0.80 | TDP1 (0.40) | TDP1TSHRALDH1A1LMNAMAPT | |
| SCHEMBL19731034 | 0.79 | RECQL (0.39) | TDP1TSHRALDH1A1LMNAMAPT | |
| SCHEMBL13443167 | 0.78 | ALDH1A1 (0.53) | TDP1TSHRALDH1A1LMNAMAPT | |
| SCHEMBL7975200 | 0.77 | TSHR (0.41) | TDP1TSHRALDH1A1LMNAMAPT | |
| SCHEMBL6442162 | 0.77 | TSHR (0.46) | TSHRLMNASMN1; SMN2GAAHSD17B10 | |
| SCHEMBL14331822 | 0.75 | TSHR (0.46) | TDP1TSHRALDH1A1MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |