Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | COMT | P21964 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 8-Aminoquinoline SCHEMBL28254141 | 0.91 | PARP1 (0.53) | PARP1ALDH1A1LMNAMMP2TSHR | |
| 8-Aminoquinoline SCHEMBL29735354 | 0.87 | LMNA (0.61) | PARP1ALDH1A1LMNAMMP2TSHR | |
| 8-Aminoquinoline SCHEMBL159694 | 0.87 | LMNA (0.61) | PARP1ALDH1A1LMNAMMP2TSHR | |
| 8-Aminoquinoline SCHEMBL27411912 | 0.85 | LMNA (0.58) | PARP1ALDH1A1LMNAMMP2TSHR | |
| 8-Aminoquinoline SCHEMBL11260984 | 0.85 | LMNA (0.58) | PARP1ALDH1A1LMNAMMP2TSHR | |
| 8-Aminoquinoline SCHEMBL29286899 | 0.84 | PARP1 (0.51) | PARP1ALDH1A1LMNAMMP2TSHR | |
| 8-Aminoquinoline SCHEMBL28170121 | 0.84 | PARP1 (0.51) | PARP1ALDH1A1LMNAMMP2TSHR | |
| 8-Aminoquinoline SCHEMBL19748791 | 0.83 | PARP1 (0.57) | PARP1ALDH1A1LMNAMMP2TSHR | |
| 8-Aminoquinoline SCHEMBL28223663 | 0.83 | PARP1 (0.53) | PARP1ALDH1A1LMNACOMTTDP1 | |
| 8-Aminoquinoline SCHEMBL28534121 | 0.83 | LMNA (0.56) | PARP1ALDH1A1LMNAMMP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047221-A | A kind of imide compound, synthetic method and its in H2O2Application in detection | 山东省医学科学院药物研究所 | 2018-05-18 | — | — | CN | claimed |