SCHEMBL28214930

SCHEMBL28214930

COC(=O)C(C(=O)OCC1c2ccccc2-c2ccccc21)C(N)I

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
FABP5 Q01469 3/20 0.44
EPHX2 P34913 1/20 0.43
FABP7 O15540 2/20 0.42
CASP3 P42574 2/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
PIN1 Q13526 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28387780 0.87 KMT2A (0.44) KMT2AFABP5EPHX2FABP7CASP3
SCHEMBL28215432 0.86 KMT2A (0.48) KMT2AFABP5EPHX2FABP7CASP3
SCHEMBL28214864 0.84 KMT2A (0.43) KMT2AFABP5EPHX2FABP7CASP3
SCHEMBL3018790 0.80 KMT2A (0.50) KMT2AFABP5EPHX2FABP7CASP3
SCHEMBL7391410 0.80 KMT2A (0.49) KMT2AFABP5EPHX2FABP7CASP3
SCHEMBL7393490 0.80 KMT2A (0.49) KMT2AFABP5EPHX2FABP7CASP3
SCHEMBL7389338 0.80 KMT2A (0.49) KMT2AFABP5EPHX2FABP7CASP3
Hydrochloric Acid SCHEMBL3020428 0.79 KMT2A (0.49) KMT2AFABP5EPHX2FABP7CASP3
SCHEMBL17753728 0.79 KMT2A (0.54) KMT2AFABP5EPHX2FABP7CASP3
SCHEMBL7037298 0.79 KMT2A (0.54) KMT2AFABP5EPHX2FABP7CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108047268-B 1-aza-5-gera-5-alkyl bicyclo [3.3.3] undecane compound, synthesis method and application 中国科学技术大学 2020-05-01 CN claimed
CN-108047268-A A kind of miscellaneous two ring of -5- alkyl [3.3.3] the hendecane class compound of 1- azepines -5- germanium, synthetic method and application 中国科学技术大学 2018-05-18 CN claimed
CN-108047268-B 1-aza-5-gera-5-alkyl bicyclo [3.3.3] undecane compound, synthesis method and application 中国科学技术大学 2020-05-01 CN disclosed
CN-108047268-A A kind of miscellaneous two ring of -5- alkyl [3.3.3] the hendecane class compound of 1- azepines -5- germanium, synthetic method and application 中国科学技术大学 2018-05-18 CN disclosed