SCHEMBL28214864

SCHEMBL28214864

C=CCOC(=O)C(C(=O)OCC1c2ccccc2-c2ccccc21)C(N)I

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
EPHX2 P34913 1/20 0.41
FABP5 Q01469 3/20 0.40
FABP7 O15540 2/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CYP3A4 P08684 1/20 0.38
RHOA P61586 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CASP3 P42574 2/20 0.38
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33377794 0.87 CASP3 (0.44) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL28214930 0.84 KMT2A (0.49) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL28215432 0.83 KMT2A (0.48) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL28387780 0.81 KMT2A (0.44) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL4728768 0.79 KMT2A (0.48) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL30729524 0.79 KMT2A (0.48) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL878241 0.79 KMT2A (0.48) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL28758363 0.76 KMT2A (0.54) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL7037298 0.76 KMT2A (0.54) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL17753728 0.76 KMT2A (0.54) KMT2AEPHX2FABP5FABP7CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108047268-B 1-aza-5-gera-5-alkyl bicyclo [3.3.3] undecane compound, synthesis method and application 中国科学技术大学 2020-05-01 CN claimed
CN-108047268-A A kind of miscellaneous two ring of -5- alkyl [3.3.3] the hendecane class compound of 1- azepines -5- germanium, synthetic method and application 中国科学技术大学 2018-05-18 CN claimed
CN-108047268-B 1-aza-5-gera-5-alkyl bicyclo [3.3.3] undecane compound, synthesis method and application 中国科学技术大学 2020-05-01 CN disclosed
CN-108047268-A A kind of miscellaneous two ring of -5- alkyl [3.3.3] the hendecane class compound of 1- azepines -5- germanium, synthetic method and application 中国科学技术大学 2018-05-18 CN disclosed