SCHEMBL28215237

SCHEMBL28215237

CCCCn1c2ccccc2c2cccc(-c3ccc(Br)s3)c21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.46
RORA P35398 2/20 0.46
RORC P51449 2/20 0.46
RORB Q92753 2/20 0.46
JAK2 O60674 1/20 0.42
MITF O75030 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 3/20 0.38
HPGD P15428 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 1/20 0.38
CNR2 P34972 3/20 0.37
CNR1 P21554 1/20 0.37
ALPL P05186 2/20 0.37
ALPG P10696 1/20 0.37
ATM Q13315 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28516192 0.80 PGR (0.48) PGRRORARORCRORBMAPT
SCHEMBL27967408 0.77 PGR (0.56) PGRRORARORCRORBALDH1A1
SCHEMBL27879273 0.73 PGR (0.51) PGRRORARORCRORBMAPT
SCHEMBL30659838 0.73 PSEN1 (0.41) JAK2MITFMAPTKMT2ANPSR1
SCHEMBL28590236 0.73 KDM4E (0.54) PGRRORARORCRORBMAPT
SCHEMBL28042024 0.73 KDM4E (0.54) PGRRORARORCRORBMAPT
SCHEMBL28778338 0.73 KDM4E (0.54) PGRRORARORCRORBMAPT
SCHEMBL19978658 0.72 PGR (0.48) PGRRORARORCRORBKMT2A
SCHEMBL27967271 0.72 CNR2 (0.50) PGRRORARORCRORBMAPT
SCHEMBL28003764 0.72 CNR2 (0.50) PGRRORARORCRORBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108191843-A Carbazolyl-containing ultraviolet absorbent and preparation method thereof 东莞理工学院 2018-06-22 CN claimed
CN-108191843-A Carbazolyl-containing ultraviolet absorbent and preparation method thereof 东莞理工学院 2018-06-22 CN disclosed