SCHEMBL28215247

SCHEMBL28215247

c1ccc(-c2ncnn2-c2cccc3ccccc23)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.42
MAPK1 P28482 1/20 0.42
GSK3B P49841 4/20 0.41
ALDH1A1 P00352 4/20 0.38
PI4KA P42356 1/20 0.38
PI4K2B Q8TCG2 1/20 0.38
PI4K2A Q9BTU6 1/20 0.38
PI4KB Q9UBF8 1/20 0.38
POLB P06746 3/20 0.37
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
P2RX7 Q99572 1/20 0.36
ADRB2 P07550 1/20 0.36
HSD17B10 Q99714 2/20 0.36
SIGMAR1 Q99720 2/20 0.36
EGLN2 Q96KS0 1/20 0.36
HTR3E A5X5Y0 1/20 0.36
HTR3B O95264 1/20 0.36
CYP1A2 P05177 1/20 0.36
HTR1A P08908 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8512480 0.78 ALDH1A1 (0.56) MAPK1GSK3BALDH1A1POLBKDM4E
SCHEMBL11115115 0.75 P2RX7 (0.47) ALDH1A1P2RX7TSHR
SCHEMBL10629073 0.74 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDADRB2HSD17B10
SCHEMBL7045196 0.73 SMN1; SMN2 (0.43) NPC1ALDH1A1PI4KAPI4K2BPI4K2A
SCHEMBL29349692 0.73 SMN1; SMN2 (0.51) GSK3BKMT2ASMN1; SMN2
SCHEMBL44765 0.73 SMN1; SMN2 (0.51) GSK3BKMT2ASMN1; SMN2
SCHEMBL28949385 0.73 SMN1; SMN2 (0.51) GSK3BKMT2ASMN1; SMN2
SCHEMBL20732635 0.71 TSHR (0.47) NPC1MAPK1ALDH1A1POLBKDM4E
SCHEMBL27659057 0.71 P2RX4 (0.46) NPC1MAPK1GSK3BPI4KAPI4K2B
SCHEMBL19196223 0.70 HSD17B2 (0.42) NPC1GSK3BALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110256495-A A kind of compound, organic electroluminescence device and display device 上海天马有机发光显示技术有限公司 2019-09-20 CN disclosed
CN-110256412-A A kind of compound, organic electroluminescence device and display device 上海天马有机发光显示技术有限公司 2019-09-20 CN disclosed
CN-105609519-B By substrate for film deposition, manufacturing method and organic EL display device 夏普株式会社 2019-08-23 CN disclosed
CN-109845404-A Display device and its manufacturing method 夏普株式会社 2019-06-04 CN disclosed
CN-109721540-A Dihydrobenzo indazole compounds, organic electroluminescence device and display device 阜阳欣奕华材料科技有限公司 2019-05-07 CN disclosed
CN-109698283-A Organic electroluminescence device and display 李现伟 2019-04-30 CN disclosed
CN-109694708-A A kind of dihydrobenzo indazole class electroluminescent organic material 李现伟 2019-04-30 CN disclosed
CN-109694709-A Dihydrobenzo indazole class electroluminescent organic material 李现伟 2019-04-30 CN disclosed
CN-109678799-A Dihydrobenzo indazole compounds, organic electroluminescence device and display device 阜阳欣奕华材料科技有限公司 2019-04-26 CN disclosed
CN-109608440-A Dihydrobenzo indazole compounds, organic electroluminescence device and display device 阜阳欣奕华材料科技有限公司 2019-04-12 CN disclosed
CN-108329254-A Dihydroanthracene compound, organic electroluminescence device and display device 王美妮 2018-07-27 CN disclosed
CN-108218763-A A kind of phenyl indene compounds, organic electroluminescence device and display device 阜阳欣奕华材料科技有限公司 2018-06-29 CN disclosed
CN-108218663-A A kind of phenyl indene compounds, organic electroluminescence device and display device 阜阳欣奕华材料科技有限公司 2018-06-29 CN disclosed
CN-108218721-A A kind of phenyl indene compounds, organic electroluminescence device and display device 阜阳欣奕华材料科技有限公司 2018-06-29 CN disclosed
CN-108218788-A A kind of phenyl indene compounds, organic electroluminescence device and display device 阜阳欣奕华材料科技有限公司 2018-06-29 CN disclosed
CN-108203406-A Benzfluorene class electroluminescent organic material, luminescent device and display 李现伟 2018-06-26 CN disclosed
CN-108203407-A Pyrene class electroluminescent organic material, luminescent device and display 李现伟 2018-06-26 CN disclosed
CN-108191744-A Benzfluorene class electroluminescent organic material, luminescent device and display 李现伟 2018-06-22 CN disclosed
CN-108047061-A Pyrene class electroluminescent organic material, luminescent device and display 李现伟 2018-05-18 CN disclosed
CN-108047130-A Benzanthracenes electroluminescent organic material, luminescent device and display 李现伟 2018-05-18 CN disclosed