SCHEMBL28215384

SCHEMBL28215384

O=C(O)CCC(=O)OC(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.45
EGLN1 Q9GZT9 4/20 0.45
ALKBH5 Q6P6C2 1/20 0.45
SUCNR1 Q9BXA5 1/20 0.45
KDM5C P41229 3/20 0.43
PHF8 Q9UPP1 3/20 0.43
KDM2A Q9Y2K7 3/20 0.43
KDM6B O15054 2/20 0.43
SLC15A2 Q16348 1/20 0.36
MAPK1 P28482 1/20 0.36
SLC13A3 Q8WWT9 1/20 0.36
OR51E2 Q9H255 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.35
TSHR P16473 4/20 0.34
KDM4E B2RXH2 2/20 0.33
FOLH1 Q04609 1/20 0.33
NFKB1 P19838 1/20 0.33
PMP22 Q01453 1/20 0.33
GABRR1 P24046 1/20 0.33
ACE P12821 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzamide SCHEMBL27750741 0.79 CYP2C19 (0.50) LMNATSHRPMP22HDAC3HDAC1
SCHEMBL22838532 0.78 TSHR (0.31) TSHR
SCHEMBL17701357 0.77
SCHEMBL9056211 0.77 LDHA (0.40) TSHR
SCHEMBL27818612 0.77
SCHEMBL17425328 0.75 ALDH1A1 (0.52) LMNATSHRFFAR3HDAC3HDAC1
SCHEMBL631111 0.75 EGLN1 (0.48) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL18747596 0.73 EGLN1 (0.46) LMNAEGLN1ALKBH5SUCNR1KDM5C
Chloromethane SCHEMBL3415691 0.73 EGLN1 (0.46) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL14816102 0.73 EGLN1 (0.46) LMNAEGLN1ALKBH5SUCNR1KDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430735-A Catalyst component for propylene polymerization, preparation method thereof, catalyst and application 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-116997578-A Prepolymerized catalyst component for olefin polymerization 巴塞尔聚烯烃意大利有限公司 2023-11-03 CN disclosed
CN-107922393-A Carrying non-aromatic P2,Novel macrocyclic form of factor XIA 百时美施贵宝公司 2018-04-17 CN disclosed