SCHEMBL28215399

SCHEMBL28215399

C=C(C)C(=O)OC(O)CC[Si](C)(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
ALDH1A1 P00352 2/20 0.33
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15941441 0.83 TSHR (0.33) TSHRALDH1A1
SCHEMBL28554386 0.83 ALDH1A1 (0.38) TSHRALDH1A1THRB
SCHEMBL27981477 0.83 ALDH1A1 (0.38) TSHRALDH1A1THRB
SCHEMBL16592838 0.81 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL27979561 0.79 THRB (0.34) TSHRALDH1A1THRB
SCHEMBL709902 0.78 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL29257398 0.76 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL14871 0.76 ALDH1A1 (0.44) TSHRALDH1A1THRB
SCHEMBL890447 0.76 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL28091462 0.76 TSHR (0.41) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107922739-A Copolymers comprising polysiloxane macromonomer units, process for their preparation and their use in coating compositions and polymeric moulding compounds 毕克化学有限公司 2018-04-17 CN disclosed