Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29824847 | 1.00 | MDM4 (0.48) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL3421848 | 1.00 | MDM4 (0.48) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL31000608 | 1.00 | MDM4 (0.48) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL13908450 | 0.90 | KMT2A (0.52) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL21764273 | 0.90 | MDM4 (0.47) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL29532800 | 0.90 | MDM4 (0.47) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL26008669 | 0.90 | KMT2A (0.52) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL31307731 | 0.90 | KMT2A (0.52) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL31000515 | 0.90 | MDM4 (0.47) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL21785029 | 0.89 | HDAC1 (0.46) | MDM4TP53CASP3EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047268-B | 1-aza-5-gera-5-alkyl bicyclo [3.3.3] undecane compound, synthesis method and application | 中国科学技术大学 | 2020-05-01 | — | — | CN | claimed |
| CN-108047268-A | A kind of miscellaneous two ring of -5- alkyl [3.3.3] the hendecane class compound of 1- azepines -5- germanium, synthetic method and application | 中国科学技术大学 | 2018-05-18 | — | — | CN | claimed |
| CN-108047268-B | 1-aza-5-gera-5-alkyl bicyclo [3.3.3] undecane compound, synthesis method and application | 中国科学技术大学 | 2020-05-01 | — | — | CN | disclosed |
| CN-108047268-A | A kind of miscellaneous two ring of -5- alkyl [3.3.3] the hendecane class compound of 1- azepines -5- germanium, synthetic method and application | 中国科学技术大学 | 2018-05-18 | — | — | CN | disclosed |