Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29532800 | 1.00 | MDM4 (0.47) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL29787093 | 0.91 | CASP3 (0.47) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL31000608 | 0.90 | MDM4 (0.48) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL28215462 | 0.90 | MDM4 (0.48) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL3421848 | 0.90 | MDM4 (0.48) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL29824847 | 0.90 | MDM4 (0.48) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL13908450 | 0.89 | KMT2A (0.52) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL31000515 | 0.89 | MDM4 (0.47) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL31307731 | 0.89 | KMT2A (0.52) | MDM4TP53CASP3EPHX2KMT2A | |
| SCHEMBL26008669 | 0.89 | KMT2A (0.52) | MDM4TP53CASP3EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746114-B2 | Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation | UNIVERSITY OF WINDSOR (CA) | 2023-09-05 | — | — | US | disclosed |
| US-11746114-B2 | Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation | UNIVERSITY OF WINDSOR (CA) | 2023-09-05 | — | — | US | disclosed |
| US-11560387-B2 | Thermally sensitive protecting groups for cysteine, and manufacture and use thereof | UNIVERSITY OF WINDSOR (CA) | 2023-01-24 | — | — | US | disclosed |
| US-20220153749-A1 | Thermally Sensitive Protecting Groups for Cysteine for Peptide Cyclization and Selective Disulfide Bond Formation | UNIVERSITY OF WINDSOR (CA) | 2022-05-19 | — | — | US | disclosed |
| US-20220024942-A1 | Thermally Sensitive Protecting Groups for Cysteine, and Manufacture and Use Thereof | UNIVERSITY OF WINDSOR | 2022-01-27 | — | — | US | disclosed |
| US-20210040105-A1 | Thermally Sensitive Protecting Groups for Cysteine, and Manufacture and Use Thereof | UNIVERSITY OF WINDSOR | 2021-02-11 | — | — | US | disclosed |
| US-20200063182-A1 | FLUOROPHORE-BASED KINASE SENSORS | ASSAYQUANT TECHNOLOGIES, INC. | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153749-A1 | Thermally Sensitive Protecting Groups for Cysteine for Peptide Cyclization and Selective Disulfide Bond Formation | PTMS, CTH, VIP | MDM4 1117/4885TP53 500/4885CASP3 611/4885 |
| US-20220024942-A1 | Thermally Sensitive Protecting Groups for Cysteine, and Manufacture and Use Thereof | CTH, TXN, CBS | MDM4 791/4885TP53 557/4885CASP3 361/4885 |
| US-11560387-B2 | Thermally sensitive protecting groups for cysteine, and manufacture and use thereof | CTH, TXN, CBS | MDM4 791/4885TP53 557/4885CASP3 361/4885 |
| US-11746114-B2 | Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation | PTMS, CTH, VIP | MDM4 1117/4885TP53 500/4885CASP3 611/4885 |
| US-20210040105-A1 | Thermally Sensitive Protecting Groups for Cysteine, and Manufacture and Use Thereof | CTH, TXN, CBS | MDM4 791/4885TP53 557/4885CASP3 361/4885 |
| US-20200063182-A1 | FLUOROPHORE-BASED KINASE SENSORS | CHEK2, CHEK1, MAP3K6 | MDM4 1017/4885TP53 875/4885CASP3 3348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.