⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1374565 | 0.71 | ALDH1A1 (0.46) | — | |
| SCHEMBL81650 | 0.69 | NISCH (0.59) | — | |
| SCHEMBL19209978 | 0.69 | ALDH1A1 (0.43) | — | |
| SCHEMBL15140518 | 0.67 | ALDH1A1 (0.48) | — | |
| SCHEMBL4964412 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL207 | 0.67 | — | — | |
| SCHEMBL68370 | 0.67 | — | — | |
| SCHEMBL28425230 | 0.67 | NISCH (0.56) | — | |
| Hydrochloric Acid SCHEMBL1536214 | 0.67 | NISCH (0.56) | — | |
| SCHEMBL188086 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341805-A | It can be used as the substituted pyridine derivate of C-fms kinase inhibitors | 詹森药业有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-105026388-B | Substituted pyridine derivatives useful as c-fms kinase inhibitors | 詹森药业有限公司 | 2018-05-18 | — | — | CN | disclosed |