Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1018588 | 0.77 | KMT2A (0.64) | MRGPRX4SRD5A2ATMALOX15GFER | |
| SCHEMBL27893362 | 0.77 | MRGPRX4 (0.47) | MRGPRX4ATMALOX15GFERADAM17 | |
| SCHEMBL28951143 | 0.77 | SRD5A2 (0.58) | SRD5A2LMNAPOLBMAPTTSHR | |
| SCHEMBL28029673 | 0.76 | PPARA (0.49) | MRGPRX4PPARASRD5A2LMNAKMT2A | |
| SCHEMBL28247826 | 0.76 | PPARG (0.59) | MRGPRX4PPARGPPARAALOX15LMNA | |
| Hydrochloric Acid SCHEMBL9015381 | 0.76 | KMT2A (0.62) | MRGPRX4SRD5A2ATMALOX15GFER | |
| SCHEMBL1950244 | 0.75 | CA12 (0.48) | SRD5A2ALOX15LMNAMAPTTSHR | |
| SCHEMBL7945362 | 0.74 | ESR1 (0.56) | SRD5A2KMT2AMEN1 | |
| SCHEMBL4235825 | 0.74 | MRGPRX4 (0.47) | MRGPRX4ATMALOX15GFERADAM17 | |
| SCHEMBL2142442 | 0.74 | PLA2G10 (0.53) | SRD5A2LMNATSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107903251-A | Pyrazole formylamine derivate as the TAAR conditioning agents for treating several conditions such as depression, diabetes and Parkinson's | 霍夫曼-拉罗奇有限公司 | 2018-04-13 | — | — | CN | disclosed |