SCHEMBL28215633

SCHEMBL28215633

CCC1=Cc2c(CC)cccc2C1[Hf](C)C

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.34
GABRB2 P47870 3/20 0.34
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30792815 0.85 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL28215649 0.83
SCHEMBL30785852 0.83 GABRA1 (0.32) GABRA1GABRB2
SCHEMBL20590593 0.82
SCHEMBL20590602 0.81
SCHEMBL20378127 0.81 DRD2 (0.30)
SCHEMBL20590687 0.79
SCHEMBL28411828 0.76 GABRA1 (0.36) GABRA1GABRB2KDM4EMEN1MAPT
SCHEMBL27524796 0.76 GABRA1 (0.36) GABRA1GABRB2KDM4EMEN1MAPT
SCHEMBL27543131 0.76 GABRA1 (0.36) GABRA1GABRB2KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110845546-A Substituted metallocene catalysts 埃克森美孚化学专利公司 2020-02-28 CN claimed
CN-117597420-A Ethylene-propylene branched copolymers useful as viscosity modifiers 埃克森美孚化学专利公司 2024-02-23 CN disclosed
CN-110845801-B Polymer composition and process for producing the same 埃克森美孚化学专利公司 2023-01-03 CN disclosed
CN-112805329-A Process for preparing a polymer composition with enhanced elasticity by employing a VTP and HMP catalyst system in a parallel process 埃克森美孚化学专利公司 2021-05-14 CN disclosed
CN-107207807-B Process for producing polymer composition 埃克森美孚化学专利公司 2020-06-16 CN disclosed
CN-107148446-B Polymer composition and process for producing the same 埃克森美孚化学专利公司 2020-06-16 CN disclosed
CN-110845801-A Polymer composition and process for producing the same 埃克森美孚化学专利公司 2020-02-28 CN disclosed
CN-110845546-A Substituted metallocene catalysts 埃克森美孚化学专利公司 2020-02-28 CN disclosed
CN-105358588-B Method and product therefrom using substitution metallocene catalyst 埃克森美孚化学专利公司 2018-05-18 CN disclosed