SCHEMBL28215905

SCHEMBL28215905

[CH2]c1ccc(-c2cccc(CN)c2)cc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.50
CFD P00746 6/20 0.48
CSNK2A1 P68400 2/20 0.47
LOXL2 Q9Y4K0 1/20 0.47
F11 P03951 2/20 0.44
TPSB2 P20231 2/20 0.44
PLG P00747 1/20 0.44
PLAU P00749 1/20 0.44
KLKB1 P03952 1/20 0.44
F7 P08709 1/20 0.44
AGXT P21549 1/20 0.42
AOC3 Q16853 3/20 0.42
SUCNR1 Q9BXA5 1/20 0.41
ADAMTS4 O75173 1/20 0.40
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
NOS2 P35228 1/20 0.40
DPP4 P27487 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28247640 0.82 TAAR1 (0.74) TAAR1CFDCSNK2A1LOXL2F11
SCHEMBL17454559 0.81 TAAR1 (0.52) TAAR1CFDCSNK2A1LOXL2F11
SCHEMBL29400616 0.80 TAAR1 (0.70) TAAR1CFDCSNK2A1LOXL2F11
SCHEMBL43554 0.80 TAAR1 (0.70) TAAR1CFDCSNK2A1LOXL2F11
SCHEMBL97189 0.80 MEN1 (0.52)
SCHEMBL28126553 0.79 TAAR1 (0.59) TAAR1CFDCSNK2A1LOXL2F11
SCHEMBL27649924 0.78 LOXL2 (0.58) TAAR1CFDCSNK2A1LOXL2F11
Hydrochloric Acid SCHEMBL29793666 0.78 TAAR1 (0.67) TAAR1CFDCSNK2A1LOXL2F11
Hydrochloric Acid SCHEMBL1237399 0.78 TAAR1 (0.67) TAAR1CFDCSNK2A1LOXL2F11
Bromide SCHEMBL1856525 0.78 TAAR1 (0.67) TAAR1CFDCSNK2A1LOXL2F11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107982266-A Carbamate compounds and its preparation and application 阿比德治疗公司 2018-05-04 CN disclosed