Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.70 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.67 |
| ▸ | AGXT | P21549 | 1/20 | 0.61 |
| ▸ | CFD | P00746 | 4/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | F11 | P03951 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43554 | 1.00 | TAAR1 (0.70) | TAAR1LOXL2AGXTCFDAOC3 | |
| Hydrochloric Acid SCHEMBL29793666 | 0.98 | TAAR1 (0.67) | TAAR1LOXL2AGXTCFDAOC3 | |
| Hydrochloric Acid SCHEMBL1237399 | 0.98 | TAAR1 (0.67) | TAAR1LOXL2AGXTCFDAOC3 | |
| Bromide SCHEMBL1856525 | 0.98 | TAAR1 (0.67) | TAAR1LOXL2AGXTCFDAOC3 | |
| SCHEMBL28247640 | 0.98 | TAAR1 (0.74) | TAAR1LOXL2AGXTCFDAOC3 | |
| SCHEMBL27799749 | 0.98 | TAAR1 (0.67) | TAAR1LOXL2AGXTCFDAOC3 | |
| SCHEMBL3791745 | 0.93 | LOXL2 (0.60) | TAAR1LOXL2AGXTCFDHRH3 | |
| SCHEMBL3794460 | 0.91 | TAAR1 (0.70) | TAAR1LOXL2AGXTCFDHRH3 | |
| Benzylamine SCHEMBL11416949 | 0.90 | LOXL2 (0.74) | TAAR1LOXL2AGXTCFDAOC3 | |
| Biphenyl SCHEMBL27410798 | 0.90 | TAAR1 (0.84) | TAAR1LOXL2AGXTHRH3PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025213277-A1 | N1-(3,4-DICHLOROPHENYL)MALEAMIDE DERIVATIVES AND THE USE THEREOF IN THE TREATMENT OF INFLAMMATORY DISORDERS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2025-10-16 | — | — | WO | disclosed |
| WO-2025076476-A2 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-04-10 | — | — | WO | disclosed |
| WO-2025064718-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-03-27 | — | — | WO | disclosed |
| CN-119212727-A | Targeted bifunctional degradants | 耶鲁大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-117003776-A | Boric acid proteasome inhibitor and application thereof | 科辉智药生物科技(深圳)有限公司 | 2023-11-07 | — | — | CN | disclosed |
| US-11759462-B2 | Spirocyclic compounds as tryptophan hydroxylase inhibitors | ALTAVANT SCIENCES GMBH | 2023-09-19 | — | — | US | disclosed |
| CN-115315272-A | Targeting difunctional degradation agent | 耶鲁大学 | 2022-11-08 | — | — | CN | disclosed |
| EP-4041262-A1 | TARGETED BIFUNCTIONAL DEGRADERS | Yale University (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-108779042-B | Ruthenium and osmium monocarbonyl catalysts | 乌迪内大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-114127050-A | Benzopyran and imidazole derivatives useful for stabilizing amyloidogenic immunoglobulin light chains | 斯克利普斯研究所 | 2022-03-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11759462-B2 | Spirocyclic compounds as tryptophan hydroxylase inhibitors | TPH1, TPH2, HTR1A | TAAR1 116/4885LOXL2 1549/4885AGXT 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.