Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPRF | P10586 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661761 | 0.84 | SLC22A6 (0.67) | SLC22A6PBRM1MAPTKDM4EAPAF1 | |
| SCHEMBL4223719 | 0.83 | SLC22A6 (0.69) | SLC22A6PBRM1MAPTNR4A2CREBBP | |
| SCHEMBL27790479 | 0.77 | MAPK1 (0.52) | SLC22A6PBRM1MAPTALDH1A1PTPRC | |
| SCHEMBL27494000 | 0.75 | PDGFRB (0.51) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL27498634 | 0.74 | SLC22A6 (0.69) | SLC22A6PBRM1MAPTKDM4EAPAF1 | |
| SCHEMBL8945241 | 0.72 | KDM4E (0.51) | SLC22A6PBRM1MAPTKDM4EAPAF1 | |
| SCHEMBL11537835 | 0.72 | KIF11 (0.45) | PBRM1MAPTKDM4EALDH1A1HTT | |
| SCHEMBL23241898 | 0.72 | SLC22A6 (0.66) | SLC22A6PBRM1MAPTKDM4EAPAF1 | |
| SCHEMBL21806575 | 0.72 | SLC22A6 (0.66) | SLC22A6PBRM1MAPTKDM4EAPAF1 | |
| SCHEMBL1822132 | 0.71 | SLC22A6 (0.65) | SLC22A6PBRM1MAPTKDM4EAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108218760-A | A kind of crystal form of Bazedoxifene Pfansteihl salt | 福建省微生物研究所 | 2018-06-29 | — | — | CN | disclosed |