Dibenzoylmethane

Dibenzoylmethane

SCHEMBL28215978

COc1ccc(C=CC(=O)O)cc1.O=C(CC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.71
ATM Q13315 1/20 0.71
BCHE P06276 1/20 0.67
CYP3A4 P08684 1/20 0.67
NFKB1 P19838 1/20 0.67
NFKB2 Q00653 1/20 0.67
RELA Q04206 1/20 0.67
GSK3B P49841 1/20 0.60
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
ALDH1A1 P00352 3/20 0.58
MAOB P27338 2/20 0.58
MAPT P10636 2/20 0.58
HSPD1 P10809 1/20 0.58
TNFRSF1A P19438 1/20 0.58
HSPE1 P61604 1/20 0.58
CYP1B1 Q16678 1/20 0.58
PTGER4 P35408 1/20 0.57
PTGER3 P43115 1/20 0.57
PTGER2 P43116 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL28282178 0.87 THRB (0.78) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL28105146 0.86 THRB (0.89) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL58700 0.84 THRB (1.00) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL12473722 0.84 THRB (1.00) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL58699 0.84 THRB (1.00) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL5330596 0.83 THRB (0.96) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL10935651 0.83 THRB (0.96) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL2298853 0.83 THRB (0.96) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL8500105 0.83 THRB (0.96) THRBATMBCHECYP3A4NFKB1
SCHEMBL747850 0.83 NPC1 (0.71) CYP3A4GSK3BMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108025196-A Water-In-Oil light screening composition with organic sunscreen actives 莱雅公司 2018-05-11 CN claimed