Benzophenone

Benzophenone

SCHEMBL28282178

COc1ccc(C=CC(=O)O)cc1.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.78
ATM Q13315 1/20 0.78
BCHE P06276 1/20 0.72
CYP3A4 P08684 1/20 0.72
NFKB1 P19838 1/20 0.72
NFKB2 Q00653 1/20 0.72
RELA Q04206 1/20 0.72
SRD5A2 P31213 1/20 0.70
MAPT P10636 3/20 0.63
MAOB P27338 3/20 0.63
MEN1 O00255 2/20 0.63
ALDH1A1 P00352 2/20 0.63
KMT2A Q03164 2/20 0.63
HSPD1 P10809 1/20 0.63
TNFRSF1A P19438 1/20 0.63
HSPE1 P61604 1/20 0.63
CYP1B1 Q16678 1/20 0.63
F3 P13726 2/20 0.60
TRPM8 Q7Z2W7 2/20 0.58
PTGER4 P35408 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17457045 0.94 THRB (0.83) THRBATMBCHECYP3A4NFKB1
SCHEMBL17457044 0.94 THRB (0.83) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL28105146 0.90 THRB (0.89) THRBATMBCHECYP3A4NFKB1
SCHEMBL9580484 0.89 CYP3A4 (0.69) THRBATMBCHECYP3A4NFKB1
SCHEMBL9580489 0.89 CYP3A4 (0.69) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL58700 0.88 THRB (1.00) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL58699 0.88 THRB (1.00) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL12473722 0.88 THRB (1.00) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL8500105 0.87 THRB (0.96) THRBATMBCHECYP3A4NFKB1
4-Methoxycinnamic Acid SCHEMBL5330605 0.87 THRB (0.96) THRBATMBCHECYP3A4NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110520100-A The manufacturing method of ultraviolet protection overlay film KAO CORP 2019-11-29 CN disclosed
CN-105392811-B Powder polymer, preparation method and its purposes as thickener 化工产品开发公司SEPPIC 2019-03-08 CN disclosed