Sulfuric Acid

Sulfuric Acid

SCHEMBL28216511

CC(=O)O.Cc1ncc[nH]1.O=S(=O)(O)O

nearest known ligand 0.61

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A known ✓ P08913 1/20 0.31
ADRA2B known ✓ P18089 1/20 0.31
ADRA2C known ✓ P18825 1/20 0.31
ALDH1A1 P00352 3/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
KDM4E B2RXH2 2/20 0.36
TBXAS1 P24557 2/20 0.34
NISCH Q9Y2I1 2/20 0.32
FDPS P14324 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
SMPD3 Q9NY59 1/20 0.31
GABRR1 P24046 1/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
MTOR P42345 1/20 0.31
ADK P55263 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28175973 0.92 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Acetic Acid SCHEMBL28292779 0.92 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Acetic Acid SCHEMBL566317 0.92 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Sulfuric Acid SCHEMBL3861627 0.92 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Sulfuric Acid SCHEMBL27700929 0.92 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Sulfuric Acid SCHEMBL28680103 0.90 ALDH1A1 (0.70) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Acetic Acid SCHEMBL28425228 0.90 ALDH1A1 (0.70) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Sulfuric Acid SCHEMBL27724090 0.90 ALDH1A1 (0.70) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Acetic Acid SCHEMBL28183765 0.90 ALDH1A1 (0.70) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Sulfuric Acid SCHEMBL27641706 0.88 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108086054-A A kind of preparation method of antistatic glaxin release paper 温州市新丰装饰材料有限公司 2018-05-29 CN claimed
CN-108086054-A A kind of preparation method of antistatic glaxin release paper 温州市新丰装饰材料有限公司 2018-05-29 CN disclosed