SCHEMBL28216801

SCHEMBL28216801

Cc1c[nH]c(=S)[nH]c1=O.[Au]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.58
KDM3B Q7LBC6 1/20 0.53
UBE2N P61088 1/20 0.46
KMT2A Q03164 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
FFAR3 O14843 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
TP53 P04637 1/20 0.37
MEN1 O00255 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
LPO P22079 1/20 0.35
PTGS1 P23219 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
POLB P06746 1/20 0.35
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25450 0.98
SCHEMBL25418259 0.98 ATAD2 (0.60) ATAD2KDM3BUBE2NKMT2ATDP1
Thymine SCHEMBL29232704 0.90 ATAD2 (0.76) ATAD2KDM3BUBE2NKMT2ATDP1
SCHEMBL28216798 0.87 ATAD2 (0.46) ATAD2KDM3BUBE2NKMT2ATDP1
SCHEMBL28211067 0.85 ATAD2 (0.47) ATAD2KDM3BUBE2NKMT2ATDP1
Thiouracil SCHEMBL4958659 0.83 TP53 (0.66) ATAD2KDM3BUBE2NKMT2ATDP1
Pyrimidine SCHEMBL29014623 0.83 ATAD2 (0.46) ATAD2KDM3BUBE2NKMT2ATDP1
SCHEMBL29041555 0.80 ATAD2 (0.43) ATAD2KDM3BUBE2NKMT2ATDP1
SCHEMBL29041552 0.79 ATAD2 (0.42) ATAD2KDM3BUBE2NKMT2ATDP1
Triphosphate SCHEMBL27943631 0.79 ATAD2 (0.42) ATAD2KDM3BUBE2NKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105860963-B Guanidine hydrochloride/6- azepines -2- thio-thymines-gold nano cluster and preparation method thereof 福建医科大学 2018-06-22 CN claimed
CN-105860959-B Arginine/6- azepines -2- thio-thymines-gold nano cluster and preparation method thereof 福建医科大学 2018-05-18 CN claimed
CN-105860959-B Arginine/6- azepines -2- thio-thymines-gold nano cluster and preparation method thereof 福建医科大学 2018-05-18 CN disclosed