Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17717585 | 0.85 | L3MBTL1 (0.42) | HTTNPSR1TDP1LMNAGFER | |
| SCHEMBL10178236 | 0.78 | HTT (0.54) | HTTNPSR1ALDH1A1MAPTTDP1 | |
| SCHEMBL24387685 | 0.74 | HTT (0.53) | HTTNPSR1ALDH1A1MAPTTDP1 | |
| SCHEMBL22730736 | 0.74 | HTT (0.56) | HTTNPSR1ALDH1A1MAPTTDP1 | |
| SCHEMBL18765190 | 0.74 | HTT (0.53) | HTTNPSR1ALDH1A1MAPTTDP1 | |
| SCHEMBL1786298 | 0.74 | HTT (0.71) | HTTNPSR1ALDH1A1MAPTTDP1 | |
| SCHEMBL2552253 | 0.73 | HTT (0.52) | HTTNPSR1ALDH1A1MAPTTDP1 | |
| SCHEMBL18764784 | 0.73 | HTT (0.52) | HTTNPSR1ALDH1A1MAPTTDP1 | |
| SCHEMBL3956902 | 0.72 | HTT (0.69) | HTTNPSR1ALDH1A1MAPTTDP1 | |
| SCHEMBL18765021 | 0.72 | HTT (0.54) | HTTNPSR1ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290878-A | NOVEL FERROPORTIN INHIBITORS | 威佛（国际）股份公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-108025084-A | Antibody Drug Conjugates (ADC) and antibody prodrug conjugates (APDC) with enzyme cleavable groups | 拜耳医药股份有限公司 | 2018-05-11 | — | — | CN | disclosed |