SCHEMBL10178236

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4154646	0.85	L3MBTL1 (0.43)	HTTNPSR1TDP1LMNACA12
	SCHEMBL22482074	0.80	MTNR1A (0.46)	ALDH1A1MAPTLMNAHPGDSMN1; SMN2
	SCHEMBL28216845	0.78	HTT (0.53)	HTTNPSR1ALDH1A1TDP1MAPT
	SCHEMBL22730736	0.78	HTT (0.56)	HTTNPSR1ALDH1A1TDP1MAPT
	SCHEMBL2552253	0.77	HTT (0.52)	HTTNPSR1ALDH1A1TDP1MAPT
	SCHEMBL6207591	0.76	MEN1 (0.51)	HTTNPSR1TDP1MAPTGAA
	SCHEMBL24095922	0.75	FAAH (0.47)	CA12CA1CA2CA9
	SCHEMBL18765190	0.75	HTT (0.53)	HTTNPSR1ALDH1A1TDP1MAPT
	SCHEMBL18764998	0.75	HTT (0.50)	HTTNPSR1ALDH1A1TDP1MAPT
	SCHEMBL2552259	0.75	HTT (0.50)	HTTNPSR1ALDH1A1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.