Chloromethane

Chloromethane

SCHEMBL28216852

C=C(C)C(=O)OCCNC.CCl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
TSHR P16473 3/20 0.48
ALDH1A1 P00352 4/20 0.43
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108325 0.96 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
Bromide SCHEMBL7209515 0.94 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Ammonia Solution, Strong SCHEMBL8131325 0.94 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Hydrochloric Acid SCHEMBL1410288 0.94 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Trimethylammonium SCHEMBL28548536 0.90 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
Sulfuric Acid SCHEMBL3273309 0.89 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
Sulfuric Acid SCHEMBL8025357 0.89 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
Trifluoroacetic Acid SCHEMBL27141601 0.88 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17307124 0.86 THRB (0.63) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17307126 0.86 THRB (0.63) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105008288-B The waste stream for adding aluminon to containing sulfate radicals reduces the concentration of sulfate radical 艺康美国股份有限公司 2018-04-24 CN disclosed