Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108325 | 0.98 | THRB (0.53) | THRBTSHRALDH1A1APEX1POLB | |
| Ammonia Solution, Strong SCHEMBL8131325 | 0.96 | THRB (0.52) | THRBTSHRALDH1A1APEX1POLB | |
| Hydrochloric Acid SCHEMBL1410288 | 0.96 | THRB (0.52) | THRBTSHRALDH1A1APEX1POLB | |
| Chloromethane SCHEMBL28216852 | 0.94 | THRB (0.50) | THRBTSHRALDH1A1APEX1POLB | |
| Trimethylammonium SCHEMBL28548536 | 0.92 | THRB (0.48) | THRBTSHRALDH1A1APEX1POLB | |
| Sulfuric Acid SCHEMBL3273309 | 0.90 | THRB (0.47) | THRBTSHRALDH1A1APEX1POLB | |
| Sulfuric Acid SCHEMBL8025357 | 0.90 | THRB (0.47) | THRBTSHRALDH1A1APEX1POLB | |
| SCHEMBL17307126 | 0.88 | THRB (0.63) | THRBTSHRALDH1A1APEX1POLB | |
| SCHEMBL17307124 | 0.88 | THRB (0.63) | THRBTSHRALDH1A1APEX1POLB | |
| SCHEMBL29094306 | 0.87 | THRB (0.44) | THRBTSHRALDH1A1APEX1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107109164-B | Adhesive composition and bonding sheet | 哈利玛化成株式会社 | 2019-06-21 | — | — | CN | disclosed |
| CN-107249886-B | Stack membrane and its manufacturing method | 东丽株式会社 | 2019-06-11 | — | — | CN | disclosed |
| CN-108441055-A | A kind of waterborne acrylic primer | 湖州富美材料科技有限公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-108348878-A | Metal particle dispersant, metal particle dispersion liquid, coating agent, cured film and adhesive resin | 哈利玛化成株式会社 | 2018-07-31 | — | — | CN | disclosed |
| CN-105026027-B | Metal particle dispersant, metal particle dispersion liquid and cured film | 播磨化成株式会社 | 2018-03-20 | — | — | CN | disclosed |
| CN-107709012-A | Stack membrane and its manufacture method | 东丽株式会社 | 2018-02-16 | — | — | CN | disclosed |
| CN-106543707-B | Low temperature resistant ultra-tough nylon composite materials and preparation method thereof | 上海耐特复合材料制品有限公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-105612227-B | Coating composition and coated article | 关西涂料株式会社 | 2017-11-24 | — | — | CN | disclosed |
| CN-107249886-A | Stack membrane and its manufacture method | 东丽株式会社 | 2017-10-13 | — | — | CN | disclosed |
| CN-105658747-B | Coating composition and coated article | 关西涂料株式会社 | 2017-09-29 | — | — | CN | disclosed |
| CN-107109164-A | Adhesive composition and bonding sheet | 哈利玛化成株式会社 | 2017-08-29 | — | — | CN | disclosed |
| CN-106543707-A | Low temperature resistant ultra-tough nylon composite materials and preparation method thereof | 上海耐特复合材料制品有限公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-105026027-A | A liquid processing mixer and method | HARIMA CHEMICALS INC | 2015-11-04 | — | — | CN | disclosed |
| CN-104718260-A | Aqueous coating composition and coating method using same | KANSAI PAINT CO LTD | 2015-06-17 | — | — | CN | disclosed |
| EP-1324885-A1 | RECORDING MEDIUM WITH NANOPARTICLES AND METHODS OF MAKING THE SAME | Kimberly-Clark Worldwide, Inc. (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002028659-A2 | RECORDING MEDIUM WITH NANOPARTICLES AND METHODS OF MAKING THE SAME | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2002-04-11 | — | — | WO | disclosed |