Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13275793 | 0.83 | MGAM (0.44) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL11135735 | 0.82 | TSHR (0.41) | TSHRALDH1A1MAPK1TDP1FGFR4 | |
| SCHEMBL18139168 | 0.80 | TSHR (0.39) | TSHRALDH1A1MAPK1TDP1FGFR4 | |
| SCHEMBL836331 | 0.80 | ALDH1A1 (0.44) | TSHRALDH1A1MAPK1TDP1FGFR4 | |
| Water SCHEMBL27576823 | 0.80 | TSHR (0.39) | TSHRALDH1A1MAPK1TDP1FGFR4 | |
| SCHEMBL7920304 | 0.78 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL1671374 | 0.78 | TSHR (0.38) | TSHRALDH1A1MAPK1TDP1 | |
| Ammonia Solution, Strong SCHEMBL28190594 | 0.78 | TSHR (0.38) | TSHRALDH1A1MAPK1TDP1TGM2 | |
| SCHEMBL29204199 | 0.77 | TSHR (0.37) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL10590343 | 0.77 | TSHR (0.37) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108003288-A | Acryloyl group glycine amide -1- vinyl -1,2,4- triazole high intensity copolymer hydrogels and preparation method thereof | 天津大学 | 2018-05-08 | — | — | CN | disclosed |
| CN-108003289-A | The application of acryloyl group glycine amide -1- vinyl -1,2,4- triazole high intensity copolymer hydrogels | 天津大学 | 2018-05-08 | — | — | CN | disclosed |