SCHEMBL836331

SCHEMBL836331

C=CC(=O)NOC(=O)CC

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
TSHR P16473 5/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
HPGD P15428 1/20 0.32
TGM2 P21980 2/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
THRB P10828 2/20 0.31
FGFR4 P22455 1/20 0.31
LMNA P02545 1/20 0.31
THRA P10827 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28001744 0.83 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL13275793 0.81 MGAM (0.44) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL27888234 0.80 ZDHHC20 (0.46) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL11135735 0.80 TSHR (0.41) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL28217419 0.80 TSHR (0.41) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL10590343 0.79 TSHR (0.37) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL28083015 0.79 MGAM (0.38) ALDH1A1TSHRMAPK1TDP1ZDHHC20
Methoxymethane SCHEMBL10590346 0.79 TSHR (0.37) ALDH1A1TSHRMAPK1TDP1ZDHHC20
Ammonia Solution, Strong SCHEMBL28082510 0.79 MGAM (0.38) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL28082944 0.79 MGAM (0.38) ALDH1A1TSHRMAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100507680-C IPS mode liquid crystal display using two sheets of negative biaxial retardation film and + C-plate LG CHEMICAL LTD (KR) 2009-07-01 CN claimed
CN-101061425-A IPS mode liquid crystal display using two sheets of biaxial negative retardation films and a +c-plate LG CHEMICAL LTD (KR) 2007-10-24 CN claimed
CN-119731560-A Contact lens having hydrogel coating thereon 爱尔康公司 2025-03-28 CN disclosed
CN-115262068-A Processing method of fadeable active tetrahedral elastic denim fabric 江苏兰朵针织服装有限公司 2022-11-01 CN disclosed
CN-109983016-A Pyrimido [5,4-b] indolizine or pyrimido [5,4-b] pyrrole biopterin compound, preparation method and the usage 中国科学院上海药物研究所 2019-07-05 CN disclosed
US-20170037286-A1 PHYSICALLY CROSSLINKABLE ADHESIVE COPOLYMER 3M INNOVATIVE PROPERTIES COMPANY 2017-02-09 US disclosed
US-8143423-B2 N-heterocyclic carbene (NHC) catalyzed synthesis of hydroxamic acids AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-03-27 US disclosed
CN-101333654-B Plasma discharge processing unit KONICA MINOLTA HOLDINGS INC 2011-06-15 CN disclosed
CN-101230215-B Active energy ray-curing coating composition ASAHI GLASS CO LTD 2010-10-20 CN disclosed
US-20100105921-A1 N-HETEROCYCLIC CARBENE (NHC) CATALYZED SYNTHESIS OF HYDROXAMIC ACIDS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-04-29 US disclosed
CN-100507680-C IPS mode liquid crystal display using two sheets of negative biaxial retardation film and + C-plate LG CHEMICAL LTD (KR) 2009-07-01 CN disclosed
CN-100368486-C Active energy ray-curable coating composition and molded article having coating thickness of cured product of the composition ASAHI GLASS CO LTD (JP) 2008-02-13 CN disclosed
CN-101061425-A IPS mode liquid crystal display using two sheets of biaxial negative retardation films and a +c-plate LG CHEMICAL LTD (KR) 2007-10-24 CN disclosed
CN-1711325-A Active energy ray-curable coating composition and molded article having coating thickness of cured product of the composition ASAHI GLASS CO LTD (JP) 2005-12-21 CN disclosed
CN-1711599-A Optical disk having a hard coat layer to which lubricity is imparted ASAHI GLASS CO LTD (JP) 2005-12-21 CN disclosed
CN-1154678-C High solids coating compositions ���ʿ����о����޹�˾ 2004-06-23 CN disclosed
CN-1398305-A Thin film forming method, article having thin film, optical film, dielectric covered electrode, and plasma discharge processing apparatus KONISHIROKU PHOTO IND (JP) 2003-02-19 CN disclosed
CN-1071364-C Process for producing transparent pigmentary quinacridones by acid swelling of premilled sub-pigmentary quinacridones in presence of organic liquid CIBA SC HOLDING AG (CH) 2001-09-19 CN disclosed
CN-1278277-A High solids coating composition SHELL INT RESEARCH (NL) 2000-12-27 CN disclosed
CN-1158874-A Process for producing transparent pigmentary quinacridones by acid swelling of premilled sub-pigmentary quinacridones in presence of organic liquid CIBA GEIGY AG (CH) 1997-09-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105921-A1 N-HETEROCYCLIC CARBENE (NHC) CATALYZED SYNTHESIS OF HYDROXAMIC ACIDS NDC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HAO2 ALDH1A1 630/4885TSHR 2717/4885MAPK1 3024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.