Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.79 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | FAAH | O00519 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13592382 | 0.81 | MAPT (0.68) | MAPTMEN1KMT2AGAAFAAH | |
| SCHEMBL15478099 | 0.79 | EPHX2 (0.77) | MAPTALDH1A1FAAH | |
| SCHEMBL23246008 | 0.79 | MEN1 (0.78) | MAPTSMN1; SMN2RECQLALDH1A1CYP2C19 | |
| SCHEMBL501924 | 0.79 | GAA (0.85) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL29675219 | 0.79 | GAA (0.85) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL10055001 | 0.79 | GAA (0.85) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL15145040 | 0.79 | EPHX2 (1.00) | — | |
| SCHEMBL16332685 | 0.78 | YAP1 (0.71) | MAPTMEN1KMT2AGAAFAAH | |
| SCHEMBL18966710 | 0.78 | YAP1 (0.67) | MAPTMEN1KMT2AGAAFAAH | |
| SCHEMBL16800289 | 0.78 | ALDH1A1 (0.66) | MAPTALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026056-A | As the 1,3,4- oxadiazole amide derivative compounds of 6 inhibitor of histone deacetylase and the pharmaceutical composition containing it | 株式会社钟根堂 | 2018-05-11 | — | — | CN | disclosed |