SCHEMBL282184

SCHEMBL282184

[CH2]c1cc(=O)oc2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.62
CA12 O43570 2/20 0.60
CA1 P00915 2/20 0.60
CA9 Q16790 2/20 0.60
ALDH1A1 P00352 4/20 0.50
MAOA P21397 2/20 0.50
HPGD P15428 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HSD17B10 Q99714 2/20 0.50
KDM4E B2RXH2 2/20 0.50
CYP3A4 P08684 2/20 0.50
GLA P06280 1/20 0.50
MAPT P10636 1/20 0.50
PGAM1 P18669 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
PRKDC P78527 2/20 0.49
LMNA P02545 3/20 0.47
RECQL P46063 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5396825 0.78 NQO1 (0.67) NQO1CA12CA1CA9ALDH1A1
SCHEMBL5538005 0.77 NQO1 (0.64) NQO1CA12CA1CA9ALDH1A1
SCHEMBL4396062 0.77 NQO1 (1.00) NQO1CA12CA1CA9ALDH1A1
SCHEMBL28661113 0.76 PRKDC (0.40) NQO1CA12CA1CA9ALDH1A1
SCHEMBL23747123 0.75 NQO1 (0.62) NQO1CA12CA1CA9ALDH1A1
SCHEMBL66891 0.75 MAOA (0.74) NQO1CA12CA1CA9ALDH1A1
SCHEMBL21645358 0.75 NQO1 (0.62) NQO1CA12CA1CA9ALDH1A1
4-Hydroxycoumarins SCHEMBL131312 0.75 CA12 (1.00) NQO1CA12CA1CA9ALDH1A1
SCHEMBL5670266 0.75 NQO1 (0.62) NQO1CA12CA1CA9ALDH1A1
SCHEMBL3547598 0.75 NQO1 (0.62) NQO1CA12CA1CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024146839-A1 PHOTOCAGED CAP ANALOGS FOR THE 5'-END OF RNAS Westfälische Wilhelms-Universität Münster (DE) 2024-07-11 WO claimed
EP-4397669-A1 PHOTOCAGED CAP ANALOGS FOR THE 5'-END OF RNAS Westfälische Wilhelms-Universität Münster (DE) 2024-07-10 EP claimed
US-11993801-B2 Base-modified nucleotides as substrates for TdT-based enzymatic nucleic acid synthesis ILLUMINA SINGAPORE PTE. LTD. (SG) 2024-05-28 US claimed
US-11897977-B2 Photolabile barbiturate compounds 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-02-13 US claimed
WO-2023119007-A1 ARTICLES HAVING A COATING INCLUDING POLYELECTROLYTES AND A PHOTOCLEAVABLE POLYMER, AND METHODS OF MAKING SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-06-29 WO claimed
EP-4185707-A1 BASE-MODIFIED NUCLEOTIDES AS SUBSTRATES FOR TDT-BASED ENZYMATIC NUCLEIC ACID Illumina Singapore Pte Ltd (SG) 2023-05-31 EP claimed
CN-115867670-A Base-modified nucleotides as substrates for TDT-based enzyme nucleic acids 伊鲁米纳新加坡有限公司 2023-03-28 CN claimed
US-11370940-B2 Adhesive article and methods of making and using the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-06-28 US claimed
EP-3746489-B1 PHOTOLABILE BARBITURATE COMPOUNDS 3M INNOVATIVE PROPERTIES CO (US) 2022-03-30 EP claimed
US-20220025421-A1 BASE-MODIFIED NUCLEOTIDES AS SUBSTRATES FOR TDT-BASED ENZYMATIC NUCLEIC ACID SYNTHESIS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-01-27 US claimed
EP-3316910-A1 TRIPLET-TRIPLET ANNIHILATION-BASED UPCONVERSION Children's Medical Center Corporation (US) 2018-05-09 EP claimed
US-20180021460-A1 PROBES AND METHODS FOR DETECTING AMYLOIDOGENIC PROTEINS ACADEMIA SINICA (TW) 2018-01-25 US claimed
WO-2017095704-A1 REDOX POLYMERIZABLE COMPOSITION WITH PHOTOLABILE REDUCING AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-06-08 WO claimed
WO-2017079189-A1 REDOX POLYMERIZABLE DENTAL COMPOSITION WITH PHOTOLABILE TRANSITION METAL COMPLEXES 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-05-11 WO claimed
WO-2017078883-A1 REDOX POLYMERIZABLE COMPOSITION WITH PHOTOLABILE TRANSITION METAL COMPLEXES 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-05-11 WO claimed
WO-2017004310-A1 TRIPLET-TRIPLET ANNIHILATION-BASED UPCONVERSION CHILDREN'S MEDICAL CENTER CORPORATION (US) 2017-01-05 WO claimed
US-20150148243-A1 METHOD FOR REVERSIBLE FIXATION OR SELECTIVE LYSIS OF CELL USING PHOTOCLEAVABLE POLYMER SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-05-28 US claimed
EP-0853628-B1 PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE FORSCHUNGSVERBUND BERLIN EV (DE) 2002-10-02 EP claimed
EP-0853628-A1 PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE Forschungsverbund Berlin e.V. (DE) 1998-07-22 EP claimed
WO-1997005155-A1 PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE FORSCHUNGSVERBUND BERLIN E.V. (DE) 1997-02-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11897977-B2 Photolabile barbiturate compounds PPOX, CBR1, CBR3 NQO1 103/4885CA12 3722/4885CA1 1575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.