Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 7/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600542 | 0.77 | P2RX7 (0.38) | GABRA2GABRB2ARMEN1KMT2A | |
| SCHEMBL16974760 | 0.74 | NOTUM (0.39) | GABRA2GABRB2ARTDP1NOTUM | |
| SCHEMBL28858824 | 0.71 | NOTUM (0.49) | ALDH1A1MEN1KMT2ATDP1NOTUM | |
| SCHEMBL28127169 | 0.69 | NOTUM (0.46) | ARALDH1A1P2RX7NOTUM | |
| SCHEMBL19585203 | 0.68 | F2RL1 (0.47) | ALDH1A1MEN1KMT2ATDP1NOTUM | |
| SCHEMBL28329509 | 0.66 | NOTUM (0.41) | GABRA2GABRB2ARNOTUM | |
| SCHEMBL2451187 | 0.66 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL16767223 | 0.65 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL16974788 | 0.63 | NOTUM (0.39) | GABRA2GABRB2ARNOTUM | |
| SCHEMBL30995064 | 0.63 | NOTUM (0.39) | GABRA2GABRB2ARNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137549-A | FXIA inhibitor derived from novel substituted glycine | 百时美施贵宝公司 | 2018-06-08 | — | — | CN | disclosed |